Drug intelligence / Profile preview

aspirin + cyclosporine

Development stage
Unknown
Lead developer
Bayer
Modality
Small Molecules
Administration
Oral, Intravenous, Rectal, Ophthalmic
01

Overview

Aspirin + cyclosporine is a combination of two small molecule drugs, each with distinct mechanisms of action. Aspirin (acetylsalicylic acid) is a non-selective cyclooxygenase (COX) inhibitor used for its analgesic, antipyretic, anti-inflammatory, and antiplatelet effects. Cyclosporine is an immunosuppressant that acts as a calcineurin inhibitor to prevent organ transplant rejection and treat autoimmune diseases by suppressing T-cell activation. This combination does not have a unique brand or product name and is not marketed as a fixed-dose formulation; it refers to the concurrent use of both agents in clinical practice.

02

Targets

PGHS-1 (Prostaglandin G/H Synthase 1)CN (Calcineurin)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)PPIA (Peptidyl-prolyl cis-trans isomerase A)

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