aspirin + meloxicam

A combination of two nonsteroidal anti-inflammatory drugs (NSAIDs). Meloxicam is a prescription NSAID that selectively inhibits COX-2 enzymes, while aspirin (acetylsalicylic acid) is an NSAID that inhibits both COX-1 and COX-2 enzymes. When taken together, these medications can interact with each other. According to the search results, concurrent treatment with aspirin can increase plasma concentrations of meloxicam, raising the maximum plasma concentration (Cmax) by approximately 25% and the area under the plasma concentration-time curve (AUC) by 10%[3]. However, these differences were not considered clinically relevant, and no adjustments of meloxicam dose should be required when coadministered with aspirin[3]. Both medications are used to treat pain and inflammation, but they have different properties. Meloxicam is primarily used for osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis[7]. Aspirin, besides its anti-inflammatory effects, also has antiplatelet properties that make it beneficial for preventing heart attacks and strokes, which meloxicam does not offer[6].

Brand names

MobicBayer AspirinEcotrin

Other names

acetylsalicylic acid + meloxicamaspirin and meloxicam