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atezolizumab + daratumumab
- Development stage
- Unknown
- Lead developer
- Janssen Pharmaceutical
- Modality
- Monoclonal Antibodies → Antibody-Based Therapeutics
- Administration
- Intravenous, Subcutaneous
01
Overview
A combination therapy consisting of atezolizumab, a humanized IgG antibody that binds PD-L1, and daratumumab, a monoclonal antibody targeting CD38. This combination aims to leverage both immune checkpoint inhibition and targeted anti-myeloma activity.
02
Targets
CD38 (Cluster of Differentiation 38)CD274 (Programmed cell death protein 1 ligand 1)
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