atorvastatin + ascorbic acid

Atorvastatin + ascorbic acid is a combination of two active ingredients: atorvastatin, a statin (HMG-CoA reductase inhibitor) used to lower cholesterol and reduce cardiovascular risk, and ascorbic acid (vitamin C), an essential nutrient with antioxidant properties. This combination has been studied for its potential synergistic effects in specific clinical settings. For example, research indicates that the combined use of oral atorvastatin and vitamin C may be more effective than atorvastatin alone in reducing the incidence of postoperative atrial fibrillation after coronary artery bypass graft surgery[2]. Additionally, cocrystal formulations of these two agents have been explored to improve dissolution rates and safety profiles in preclinical models[3]. Atorvastatin works by inhibiting HMG-CoA reductase, thereby lowering LDL cholesterol and triglycerides while increasing HDL cholesterol[5][7]. Ascorbic acid acts primarily as an antioxidant and supports various enzymatic reactions.

Other names

Atorvastatin-Ascorbic acidAtorvastatin and Ascorbic Acid for CIN Prevention