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Atorvo+
- Development stage
- Unknown
- Lead developer
- Indication Bioscience
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Atorvo+ is an investigational fixed-dose combination therapy being developed by Indication BioScience for the treatment of coronary heart disease and dyslipidemias, including hypercholesterolemia and atherosclerosis. It consists of atorvastatin, a small molecule HMG-CoA reductase inhibitor, and a proprietary orally active solid form of cannabidiol (CBD). The combination is designed to improve cholesterol-lowering outcomes and enhance patient adherence by addressing statin-associated side effects, such as muscle pain and metabolic issues, through CBD's anti-inflammatory and metabolic-modulating properties. It is currently in Phase 1 clinical development to assess safety, tolerability, and pharmacokinetics.
- Brand names
- Atorvo+
- Other names
- Atorvo Plusatorvastatin + cannabidiolatorvastatin + CBD
02
Targets
CNR1 (Cannabinoid receptor 1)HMGCR (3-hydroxy-3-methylglutaryl-coenzyme A reductase)
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