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autologous adipose-derived stromal vascular fraction (Bangladesh Laser & Cell Surgery Institute & Hospital)
- Development stage
- Unknown
- Lead developer
- Bangladesh Laser & Cell Surgery Institute & Hospital
- Modality
- Stem Cell Therapies → Cell Therapies
- Administration
- Intravenous
01
Overview
SVF containing autologous non-expanded ADSC is an autologous cell therapy investigational product developed by the Bangladesh Laser & Cell Surgery Institute & Hospital. It consists of the stromal vascular fraction (SVF) freshly isolated from a patient's own subcutaneous adipose tissue through a process of enzymatic digestion and centrifugation, without subsequent cell culture expansion. This heterogeneous mixture contains adipose-derived stem cells (ADSCs), endothelial progenitor cells, hematopoietic stem cells, and various immune cells. The therapy is administered intravenously and is being investigated for the treatment of Chronic Kidney Disease (CKD) stages 3-5. It is hypothesized that the ADSCs within the SVF exert regenerative, anti-fibrotic, and paracrine effects to improve renal function and slow disease progression.
- Other names
- SVF containing autologous non-expanded ADSCautologous adipose-derived mesenchymal stromal cellsstromal vascular fractionSVFautologous non-expanded ADSC
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