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autologous adipose tissue-derived mesenchymal stem cells (Seoul National University Hospital)
- Development stage
- Unknown
- Lead developer
- Seoul National University Hospital
- Modality
- Stem Cell Therapies → Cell Therapies
- Administration
- Intratendinous
01
Overview
This investigational cell therapy involves the intratendinous injection of autologous adipose tissue-derived mesenchymal stem cells (AD MSCs) for the treatment of rotator cuff disease, specifically partial-thickness rotator cuff tears. Developed by researchers at Seoul National University Hospital and SMG-SNU Boramae Medical Center, the treatment utilizes the patient's own mesenchymal stem cells harvested from fat tissue. The therapy aims to improve shoulder function and relieve pain by promoting the regeneration of the rotator cuff tendon. Clinical evaluation has included a Phase 1 dose-escalation study assessing safety and efficacy across low, mid, and high-dose cohorts.
- Other names
- autologous adipose tissue-derived MSCsAD-MSCsautologous adipose tissue derived Mesenchymal Stem Cells-Seoul National University Hospital-rotator cuff disease
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