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autologous bone marrow mesenchymal stem cells (Zhujiang Hospital)
- Development stage
- Unknown
- Lead developer
- Southern Medical University Zhujiang Hospital
- Modality
- Stem Cell Therapies → Cell Therapies
- Administration
- Injection
01
Overview
Autologous bone marrow mesenchymal stem cells (BMSCs) are an investigational cell therapy being developed by Zhujiang Hospital for the treatment of ischemic stroke during the rehabilitation period. This therapy involves harvesting multipotent stromal cells from a patient's own bone marrow, which are then expanded in vitro and re-administered to the patient. BMSCs are characterized by the expression of surface markers such as CD73, CD90, and CD105. The therapeutic mechanism is multifaceted, involving the promotion of angiogenesis, the secretion of neurotrophic factors to support neuronal survival, the inhibition of apoptosis, and the modulation of the inflammatory immune response to facilitate neural repair and functional recovery.
- Other names
- autologous bone marrow mesenchymal stem cellsautologous BMSCsautologous bone marrow-derived mesenchymal stem cells
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