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Autologous CD34+ cell injection is an experimental cell therapy being developed by the Foundation for Biomedical Research and Innovation at Kobe (FBRI) for the treatment of chronic ischemic stroke. The procedure involves isolating CD34-positive hematopoietic stem and progenitor cells from the patient's own body and delivering them via intra-carotid injection to the site of brain injury. These cells are hypothesized to promote vascular regeneration (angiogenesis) and provide neurotrophic support, thereby facilitating the repair of damaged neural tissue and improving functional outcomes in patients suffering from long-term effects of stroke. The program is currently in the preclinical stage of development.
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