Drug intelligence / Profile preview

Autologous stromal vascular fraction (Swiss Medica)

Development stage
Unknown
Lead developer
Swiss Medica
Modality
Stem Cell Therapies → Cell Therapies
Administration
Intraarticular
01

Overview

This autologous cell therapy consists of the stromal vascular fraction (SVF) derived from a patient's own adipose tissue, developed by Swiss Medica XXI Century S.A. for the treatment of knee osteoarthritis. The therapeutic process involves extracting lipoaspirate via liposuction, followed by enzymatic digestion to isolate the SVF, which contains a heterogeneous population of cells including mesenchymal stem cells (MSCs), endothelial cells, and immune cells. Administered as a single intraarticular injection, the SVF cells exert anti-inflammatory and regenerative effects within the joint environment to alleviate pain and potentially repair cartilage damage. The therapy is currently being evaluated in a Phase 2 clinical trial (NCT04050111) to assess its safety and effectiveness in reducing symptoms of knee joint arthrosis.

Other names
SVFAutologous SVFAdipose-derived stromal vascular fraction

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