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autologous umbilical cord blood (Sheba Medical Center, f110c2)
- Development stage
- Unknown
- Lead developer
- Sheba Medical Center
- Modality
- Stem Cell Therapies → Cell Therapies
- Administration
- Intravenous
01
Overview
This refers to an investigational autologous cell therapy being studied at Sheba Medical Center in Israel for the treatment of autism spectrum disorder (ASD). The therapy involves a single intravenous infusion of the patient's own umbilical cord blood that was banked at birth. As a biologic therapy, it consists of autologous cells hypothesized to work by modulating inflammatory processes in the brain through paracrine signaling. The treatment aims to reduce neuroinflammation and regulate aberrant neural connectivity pathways associated with autism. Sheba Medical Center has conducted Phase II clinical trials evaluating the efficacy of this approach in children aged 1.5 to 12 years.
- Other names
- autologous umbilical cord blood cellsautologous UCB
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