Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
autologous umbilical cord blood cells (University of Florida)
- Development stage
- Discontinued
- Lead developer
- University of Florida
- Modality
- Stem Cell Therapies → Cell Therapies
- Administration
- Intravenous
01
Overview
Autologous umbilical cord blood (UCB) is an experimental cell therapy developed by the University of Florida for the treatment of newly diagnosed type 1 diabetes mellitus in children. The therapy involves a single intravenous infusion of the patient's own stored umbilical cord blood, which contains a heterogeneous population of cells including hematopoietic stem cells, mesenchymal stem cells, and regulatory T cells (Tregs). The primary therapeutic goal is to modulate the autoimmune response and preserve residual pancreatic beta-cell function and endogenous insulin production. Although early pilot studies (NCT00305344) demonstrated the safety of the procedure, they failed to show significant efficacy in slowing the decline of C-peptide levels compared to standard care, leading to the termination of this specific investigational approach.
- Other names
- autologous umbilical cord blood transfusionUCB cell therapyautologous cord blood cells
Beyond the preview
Go deeper on autologous umbilical cord blood cells (University of Florida).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on autologous umbilical cord blood cells (University of Florida).