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AV-COVID-19 + GM-CSF
- Development stage
- Unknown
- Lead developer
- Aivita Biomedical
- Modality
- Cytokines & Interferons → Recombinant Proteins and Enzymes, Vaccines & Immunotherapeutics
- Administration
- Intramuscular
01
Overview
**AV-COVID-19 + GM-CSF** is a combination approach under investigation for the treatment or prevention of COVID-19. AV-COVID-19 refers to a recombinant, protein-based COVID-19 vaccine developed by Aivita Biomedical, while GM-CSF (granulocyte-macrophage colony-stimulating factor) is a cytokine that modulates immune responses. In combination, the vaccine is formulated or co-administered with GM-CSF as an adjuvant to enhance immunogenicity. GM-CSF stimulates the differentiation and activation of myeloid lineage cells, facilitating more robust immune responses. Combination use with COVID-19 vaccines is hypothesized to improve vaccine efficacy, particularly cellular immunity, though definitive clinical evidence is not yet available for this particular combination.
- Brand names
- AV-COVID-19AV-COVID19AV-COVID 19
- Other names
- AV-COVID-19 + GM-CSF
02
Targets
SARS-CoV-2 spike
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