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Avocado Soy Unsaponifiables (ASU) are extracts derived from a mixture of avocado and soybean oils. They are primarily used for treating osteoarthritis due to their anti-inflammatory properties, which help reduce joint swelling and promote cartilage repair. ASU is often classified as a Symptomatic Slow-Acting Drug in Osteoarthritis (SYSADOA). It contains phytosterols like β-sitosterol, campesterol, and stigmasterol, tocopherols, and other unsaponifiable compounds. The mechanism of action involves inhibiting inflammatory cytokines and promoting collagen synthesis, thereby protecting cartilage.
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