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azelaic acid + citric acid + salicylic acid + ascorbic acid
- Development stage
- Unknown
- Lead developer
- Sesderma
- Modality
- Small Molecules
- Administration
- Topical
01
Overview
This combination chemical peel is a topical dermatological formulation primarily developed for the treatment of hyperpigmentation disorders, including melasma and post-inflammatory hyperpigmentation. The formulation synergistically combines the keratolytic and anti-inflammatory properties of **salicylic acid** (a beta-hydroxy acid) with the depigmenting and antibacterial effects of **azelaic acid**. **Citric acid** (an alpha-hydroxy acid) provides additional exfoliation and antioxidant benefits, while **ascorbic acid** (Vitamin C) acts as a potent antioxidant and tyrosinase inhibitor to brighten the skin and reduce melanin production. Developed by **Sesderma** (under the **Mediderma** professional brand), this specific combination is typically applied in a clinical setting to promote epidermal renewal, inhibit melanogenesis, and improve overall skin texture and tone.
- Brand names
- Melaspeel
- Other names
- azelaic acid + citric acid + salicylic acid + ascorbic acidMediderma MelaspeelSesderma Melaspeel
02
Targets
TYR (Tyrosinase)
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