azelaic acid + salicylic acid

Azelaic acid + salicylic acid is a topical combination therapy used primarily for the treatment of acne and related skin conditions. Azelaic acid is a dicarboxylic acid with antimicrobial and anti-inflammatory properties, effective in reducing inflammation, redness, and hyperpigmentation associated with acne and rosacea. It works by inhibiting the growth of *Cutibacterium acnes* (formerly *Propionibacterium acnes*) and normalizing keratinization. Salicylic acid is a beta-hydroxy acid (BHA) that acts as a keratolytic agent, promoting exfoliation by breaking down intercellular bonds in the stratum corneum to unclog pores and prevent new lesions. The combination leverages azelaic acid’s anti-inflammatory effects with salicylic acid’s pore-clearing action for enhanced efficacy against both inflammatory and non-inflammatory acne lesions[1][6]. This dual-action approach also helps address post-acne hyperpigmentation while minimizing irritation compared to other peeling agents[1][3][6].

Brand names

ANUBISMED