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azithromycin + doxycycline
- Development stage
- Unknown
- Lead developer
- Pfizer
- Modality
- Small Molecules
- Administration
- Oral, Intravenous
01
Overview
A combination of two antibiotics - azithromycin (a macrolide antibiotic) and doxycycline (a tetracycline antibiotic). Both drugs inhibit bacterial protein synthesis but through different mechanisms. This combination has shown enhanced efficacy compared to monotherapy in treating conditions such as non-gonococcal urethritis, severe scrub typhus, and has demonstrated potential in inhibiting cancer stem cell propagation.
- Other names
- Azithromycin plus DoxycyclineAzithromycin and Doxycycline
02
Targets
mt-SSU (Small mitochondrial ribosomal subunit)mt-LSU (Large mitochondrial ribosomal subunit)Bacterial RibosomeBacterial 50S ribosomal subunit
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