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Drug intelligence / Profile preview
azithromycin + oral rehydration salts
- Development stage
- Unknown
- Lead developer
- Tabros
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Zatrik ORS is a combination product manufactured by Tabros Pharma, typically used for the management of infectious diarrhea and associated dehydration. It contains **azithromycin**, a macrolide antibiotic that inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit of susceptible microorganisms, and **oral rehydration salts (ORS)**, which are used to prevent or treat fluid loss. The ORS component utilizes the sodium-glucose cotransporter 1 (SGLT1) in the small intestine to optimize the absorption of water and electrolytes. While the provided context lists 'Zatrik ORS' as a single formulation, it appears to be a concatenation of two separate Tabros products: the antibiotic Zatrik and the rehydration salt Tab-ORS.
- Brand names
- Zatrik ORS
- Other names
- ZatrikTab-ORS
02
Targets
SLC5A1 (Sodium Glucose Cotransporter 1)Bacterial 50S ribosomal subunit
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