Drug intelligence / Profile preview

bacillus subtilis + enterococcus faecalis

Development stage
Preclinical
Lead developer
Hanmi Pharmaceutical
Modality
Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration
Oral
01

Overview

Bacillus subtilis + Enterococcus faecalis is a combination probiotic product used to support gut health. The product contains live bacterial strains of Bacillus subtilis and Enterococcus faecalis, which are considered beneficial bacteria naturally found in the human gut. This combination is used to treat and prevent gastrointestinal issues such as diarrhea, constipation, and irritable bowel syndrome (IBS) by modulating the intestinal microbiota. [1-1, 1-11, 8] It is also being studied for preventing ventilator-associated pneumonia. [7, 12] The product is available in different formulations, including granules and capsules. It is marketed under various brand names, such as Mamiai (妈咪爱) and Meichangan (美常安) by Beijing Hanmi Pharmaceutical. [2, 3, 8]

Brand names
妈咪爱Mamiai美常安Medilac
Other names
枯草杆菌二联活菌

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