bacitracin + lidocaine + neomycin + polymyxin b

This is a **combination topical drug** containing **bacitracin**, **neomycin**, and **polymyxin B**—all antibiotics—with the addition of **lidocaine**, a local anesthetic[5][7][8]. It is used to **prevent and treat bacterial skin infections** associated with minor wounds, cuts, scrapes, and burns, while providing **pain relief** via the anesthetic effect of lidocaine[5][7][9]. - **Bacitracin** inhibits bacterial cell wall synthesis by interfering with dephosphorylation of lipid carrier molecules[5][7]. - **Neomycin** is an aminoglycoside antibiotic that inhibits protein synthesis by binding to the 30S ribosomal subunit[5][7]. - **Polymyxin B** disrupts bacterial cell membranes by interacting with phospholipids[5][7]. - **Lidocaine** blocks sodium channels, preventing nerve impulse transmission and producing localized numbness[5][7][8]. This combination offers broad-spectrum antibacterial coverage (Gram-positive and Gram-negative bacteria) and is applied topically in ointment form; it is available over-the-counter in various regions[5][7][8][9]. Primary indications are prevention and treatment of skin infection and pain relief in minor injuries.

Brand names

Lanabiotic Ointment

Other names

bacitracin+lidocaine+neomycin+polymyxin bneomycin/polymyxin B/bacitracin/lidocainetriple antibiotic ointment with lidocaine