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bacteriophage complex (PHARAOH trial)
- Development stage
- Unknown
- Lead developer
- University Clinical Hospital n.a. V.V. Vinogradov
- Modality
- Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
01
Overview
A bacteriophage complex drug is being evaluated in the Phase 3 PHARAOH trial as an adjunct to standard antibiotic therapy for patients with infective endocarditis. The developer is the University Clinical Hospital n.a. V.V. Vinogradov. Bacteriophages are naturally occurring viruses that infect and lyse specific bacteria, offering a potential therapeutic strategy against bacterial infections, particularly those that are resistant to antibiotics or associated with biofilms.
- Other names
- bacteriophage complex drug
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