Drug intelligence / Profile preview

banxia + houpu

Development stage
Unknown
Lead developer
Guang'anmen Hospital
Modality
Small Molecules
Administration
Oral
01

Overview

Banxia + Houpu is a traditional Chinese medicine (TCM) herb pair consisting of Pinellia ternata (Banxia) and Magnolia officinalis (Houpu). This combination serves as the functional core of the classic formula Banxia Houpu Tang and is being developed and studied by Guang'anmen Hospital of the China Academy of Chinese Medical Sciences for the treatment of subclinical hypothyroidism (SCH). The therapeutic mechanism involves the regulation of the hypothalamic-pituitary-thyroid (HPT) axis, specifically by modulating thyroid-stimulating hormone (TSH) and thyrotropin-releasing hormone (TRH) signaling. Additionally, the combination exhibits anti-inflammatory properties, reducing levels of systemic cytokines such as tumor necrosis factor-alpha (TNF-α) and interleukin-6 (IL-6), which are often implicated in thyroid dysfunction. It is particularly indicated for patients whose hypothyroidism is associated with TCM syndromes of phlegm-qi stagnation.

Other names
Banxia Houpu TangPinellia and Magnolia Bark DecoctionBHT
02

Targets

TRHR (Thyrotropin-releasing hormone receptor)TSHR (Thyroid-stimulating hormone receptor)

Beyond the preview

Go deeper on banxia + houpu.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on banxia + houpu.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call