Drug intelligence / Profile preview

BARS13 (Advaccine Biotechnology)

Development stage
Unknown
Lead developer
Advaccine Biotechnology
Modality
Recombinant Proteins and Enzymes, Small Molecules, Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

**BARS13** is an investigational recombinant respiratory syncytial virus vaccine developed by Advaccine Biopharmaceuticals Suzhou for prevention of respiratory syncytial virus infection. The intramuscular vaccine contains recombinant, non-glycosylated respiratory syncytial virus attachment glycoprotein G produced in *Escherichia coli* as its antigenic component, together with cyclosporine as an immunomodulatory component. It is designed to induce RSV G protein-specific immune responses while using cyclosporine to modulate T-cell responses associated with the historical risk of vaccine-enhanced disease. BARS13 has completed Phase 1 evaluation in healthy adults and a randomized Phase 2 safety and immunogenicity study in adults aged 60 to 80 years.

Other names
BARS-13BARS13BARS 13
02

Targets

RSV G (Respiratory syncytial virus attachment glycoprotein)

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