bazedoxifene + conjugated estrogens

Bazedoxifene + conjugated estrogens is a fixed-dose combination oral medication used in postmenopausal women with an intact uterus to treat moderate to severe vasomotor symptoms (such as hot flashes) and to prevent postmenopausal osteoporosis. Bazedoxifene is a selective estrogen receptor modulator (SERM) that acts as an antagonist in uterine tissue, reducing the risk of endometrial hyperplasia associated with estrogen therapy. Conjugated estrogens are a mixture of naturally occurring estrogen hormones that act as agonists at estrogen receptors, alleviating menopausal symptoms and helping maintain bone density. The combination provides the benefits of hormone replacement while minimizing the need for progestins and reducing certain risks associated with unopposed estrogen therapy[1][3][4][5][8].

Brand names

DuaveeDuavive

Other names

bazedoxifene/conjugated estrogensconjugated estrogens/bazedoxifene