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BCG vaccine + Yellow Fever vaccine
- Development stage
- Unknown
- Lead developer
- South Australia Health and Medical Research Institute
- Modality
- Vaccines & Immunotherapeutics
- Administration
- Intradermal, Subcutaneous
01
Overview
This combination refers to the co-administration of the Bacillus Calmette-Guérin (BCG) vaccine and the Yellow Fever vaccine, specifically within the context of clinical research conducted by the South Australian Health and Medical Research Institute (SAHMRI). The BCG vaccine is a live-attenuated strain of *Mycobacterium bovis* used primarily for the prevention of tuberculosis, while the Yellow Fever vaccine is a live-attenuated viral vaccine (typically the 17D strain). The study investigates how the gut microbiota influences the immune response to these vaccines, focusing on both the specific protection against tuberculosis and the non-specific 'trained immunity' effects that BCG may provide against heterologous challenges like the Yellow Fever virus.
- Other names
- BCG and Yellow Fever vaccine co-administrationBCG vaccine + Yellow Fever vaccine
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