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beclometasone dipropionate + chlorhexidine dihydrochloride
- Development stage
- Unknown
- Lead developer
- Chiesi
- Modality
- Small Molecules
- Administration
- Inhalation
01
Overview
The combination of beclometasone dipropionate and chlorhexidine dihydrochloride is not a standard pharmaceutical product for the treatment of asthma. Beclometasone dipropionate is a synthetic glucocorticoid corticosteroid used as an anti-inflammatory agent in respiratory and dermatological conditions. Chlorhexidine dihydrochloride is a biguanide antiseptic used for its broad-spectrum antimicrobial properties, typically in topical or oral hygiene products. Based on the provided trial context involving Chiesi and the comparison of HFA and CFC pMDIs (Clenil Compositum 250), the name provided appears to be an error for the fixed-dose combination of **beclometasone dipropionate and salbutamol**. In that intended combination, beclometasone serves as an inhaled corticosteroid (ICS) to manage airway inflammation, while salbutamol acts as a short-acting beta-2 adrenergic receptor agonist (SABA) to provide bronchodilation. Chiesi developed an HFA-propelled version of this combination to replace the older CFC-propelled Clenil Compositum formulation.
- Other names
- beclometasone dipropionate + chlorhexidine dihydrochloride
02
Targets
GR (Glucocorticoid receptor)
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