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beclometasone dipropionate + formoterol fumarate
- Development stage
- Unknown
- Lead developer
- Chiesi
- Modality
- Small Molecules
- Administration
- Inhalation
01
Overview
Beclometasone dipropionate + formoterol fumarate is an inhaled, extrafine fixed-dose combination of an inhaled corticosteroid and a long-acting beta-2 adrenergic agonist developed by Chiesi. Beclometasone dipropionate is a prodrug corticosteroid whose active metabolite exerts anti-inflammatory activity through the glucocorticoid receptor, while formoterol provides rapid and sustained bronchodilation through beta-2 adrenergic receptor agonism. The combination is supplied as pressurized metered-dose inhalation aerosol and dry-powder inhalation formulations for maintenance treatment of asthma and for symptomatic treatment of chronic obstructive pulmonary disease in approved markets.
- Brand names
- AlabasterBeklometason/Formoterol CiplaCombairFostairFostair NEXThalerFosterFoster NEXThalerFormodualFormodual NEXThalerInnovairInnovair NEXThalerInuvairInuvair NEXThalerInuxairKantos Master
- Other names
- BDP/FBDP/FFbeclomethasone dipropionate + formoterol fumaratebeclomethasone dipropionate/formoterol fumaratebeclometasone dipropionate/formoterol fumaratebeclometasone/formoterolformoterol and beclometasone
02
Targets
GR (Glucocorticoid receptor)ADRB2 (β2)
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