Drug intelligence / Profile preview

benfotiamine + folic acid + mecobalamin + pyridoxine + thioctic acid

Development stage
Unknown
Lead developer
Stevia Pharmaceuticals
Modality
Small Molecules
Administration
Oral
01

Overview

Mecxin-BT is a fixed-dose combination pharmaceutical product developed by Stevia Pharmaceuticals, primarily indicated for the management of diabetic neuropathy and peripheral neuropathy. The formulation consists of five active ingredients: mecobalamin (a neuroactive form of Vitamin B12), benfotiamine (a lipid-soluble thiamine derivative), thioctic acid (alpha-lipoic acid), pyridoxine (Vitamin B6), and folic acid. Mecobalamin facilitates the synthesis of the myelin sheath and promotes axonal regeneration. Benfotiamine helps prevent the formation of advanced glycation end products (AGEs) by activating the enzyme transketolase. Thioctic acid serves as a potent antioxidant that improves endoneurial blood flow and nerve conduction. Pyridoxine and folic acid act as essential cofactors in nerve metabolism and homocysteine regulation. Together, these components work synergistically to alleviate symptoms such as pain, numbness, and tingling associated with chronic nerve damage.

Brand names
Mecxin-BT
Other names
Mecxin-BT Capsules
02

Targets

DDC (Aromatic L-amino acid decarboxylase)MTHFR (Methylenetetrahydrofolate reductase)MTR (Methionine synthase)PDH (Pyruvate dehydrogenase complex)TKT (Transketolase)

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