benzalkonium chloride + benzocaine

Benzalkonium chloride + benzocaine is an over-the-counter topical combination medication used primarily to treat cold sores and fever blisters. It combines two active ingredients with complementary actions: - Benzalkonium chloride is a quaternary ammonium compound that acts as an antiseptic, helping to prevent infection at the site of application. - Benzocaine is an ester local anesthetic that provides temporary pain relief by blocking nerve signal transmission through inhibition of sodium channels in neuronal membranes. This combination works by numbing the affected area (benzocaine) and reducing the risk of secondary infection (benzalkonium chloride). It is available in various topical forms, including creams and single-dose solutions. The product is marketed under brand names such as Orajel Single Dose and Orajel Cold Sore[3][4][5].

Brand names

Orajel Single DoseOrajel Cold Sore