benzalkonium chloride + ethanol

Benzalkonium chloride + ethanol is a synergistic topical antiseptic combination used primarily for hand hygiene and skin disinfection. Ethanol, typically present in concentrations between 60% and 80%, acts rapidly to kill a broad spectrum of bacteria, viruses, and fungi by denaturing essential proteins and dissolving lipid membranes. Benzalkonium chloride, a quaternary ammonium compound, complements this by providing persistent antimicrobial activity after the alcohol has evaporated. It works by adsorbing to and disrupting the cytoplasmic membrane of microorganisms, leading to leakage of cellular contents. This combination is widely utilized in healthcare settings to reduce the risk of healthcare-associated infections and in consumer products for general sanitization.

Other names

Ethanol and benzalkonium chloride antisepticAlcohol-based hand rub with benzalkonium chloride