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A combination topical agent composed of **benzalkonium chloride**, a cationic surfactant and biocidal antimicrobial widely used as an antiseptic, and **menthone glycerin acetal**, a cooling agent that provides a long-lasting skin icing and freshening sensation. Benzalkonium chloride acts via disruption of microbial cell membranes, resulting in bactericidal and fungicidal effects[2][4][7]. Menthone glycerin acetal serves as a non-irritating cooling compound, enhancing user comfort by providing rapid cooling and soothing relief to the skin, often preferred over menthol in topical preparations for its lower irritation potential and longer-lasting effect[3]. This combination is used as an over-the-counter topical product to relieve pain and itching (e.g., for cold sores, minor cuts, scrapes, burns, or chapped lips), and to help protect against skin infection[1].
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