benzydamine + dichlorobenzyl alcohol

DoriDuo is a fixed-dose combination lozenge containing benzydamine hydrochloride and 2,4-dichlorobenzyl alcohol, developed by MEDICE Arzneimittel Puetter for the symptomatic treatment of acute pharyngitis. Benzydamine is a locally acting non-steroidal anti-inflammatory drug (NSAID) that provides analgesic, anti-inflammatory, and local anesthetic effects. Unlike traditional NSAIDs, benzydamine primarily acts by inhibiting the production of pro-inflammatory cytokines, such as tumor necrosis factor-alpha (TNF-α) and interleukin-1β (IL-1β), and by stabilizing cell membranes. It also exhibits local anesthetic properties through the inhibition of voltage-gated sodium channels. 2,4-dichlorobenzyl alcohol is a mild antiseptic with broad-spectrum antimicrobial activity that helps reduce the microbial load in the oral cavity and pharynx. The combination is designed to provide rapid relief from sore throat pain while addressing underlying inflammation and infection.

Brand names

DoriDuo

Other names

benzydamine hydrochloride + 2,4-dichlorobenzyl alcohol