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beta-carotene + vitamin C + vitamin E + magnesium

Development stage
Preclinical
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
Administration
Oral
01

Overview

A combination product containing beta-carotene, vitamin C (ascorbic acid), vitamin E (tocopherol), and magnesium. This formulation is primarily used as a dietary supplement for its antioxidant properties and potential to reduce oxidative stress. Each component has a distinct mechanism of action: - Beta-carotene is a provitamin A carotenoid with antioxidant activity. - Vitamin C is a water-soluble antioxidant that scavenges free radicals. - Vitamin E is a fat-soluble antioxidant protecting cell membranes from oxidative damage. - Magnesium acts as an essential mineral involved in numerous enzymatic reactions, including those related to cellular defense against oxidative injury. This combination has been studied for its potential role in preventing noise-induced hearing loss and temporary threshold shifts due to its synergistic antioxidative effects[2][3]. However, clinical trials have shown mixed results regarding efficacy in real-world settings[3].

Brand names
Soundbites
Other names
ACEMg formulation
02

Targets

H2O2 (Hydrogen peroxide)

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