Drug intelligence / Profile preview

beta-hydroxy-beta-methylbutyrate + vitamin d

Development stage
Unknown
Lead developer
Metabolic Technologies Inc.
Modality
Small Molecules
Administration
Oral
01

Overview

myHMB + Vitamin D is a combination nutritional supplement developed by Metabolic Technologies Inc. consisting of calcium beta-hydroxy-beta-methylbutyrate (HMB) and vitamin D3 (cholecalciferol). HMB, a metabolite of the essential amino acid leucine, promotes muscle health by stimulating protein synthesis through the mTOR pathway and reducing protein breakdown via the ubiquitin-proteasome system. Vitamin D3 is included to optimize muscle function and bone health, particularly in older adults where vitamin D insufficiency is prevalent. The combination is primarily investigated for its ability to enhance muscular strength, increase lean muscle mass, and improve physical functionality in elderly populations, especially when combined with resistance exercise.

Brand names
myHMB + Vitamin D
Other names
beta-hydroxy-beta-methylbutyrate + vitamin d-Metabolic Technologies Inc.HMB + Vitamin Dcalcium HMB + vitamin D3beta-hydroxy-beta-methylbutyrate + cholecalciferol
02

Targets

VDR (Vitamin D receptor)

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