betamethasone + local anesthetic

This is a combination injectable product containing the corticosteroid betamethasone (typically as both sodium phosphate and acetate esters) and a local anesthetic (commonly lidocaine or bupivacaine). The corticosteroid component acts by suppressing inflammation through inhibition of multiple inflammatory cytokines and immune mediators. The local anesthetic component stabilizes neuronal membranes by inhibiting ionic fluxes required for initiation and conduction of nerve impulses, resulting in localized numbness. This combination is used for intra-articular, intralesional, perineural, or infiltration injections to provide both rapid pain relief from the anesthetic and prolonged anti-inflammatory effects from the steroid. It is indicated for conditions such as arthritis flares, bursitis, tenosynovitis, acute gouty arthritis exacerbations, soft tissue inflammation/injury management, and other musculoskeletal disorders[2][4][5]. Caution is advised due to potential chondrotoxicity when injected into joints[1], as well as possible precipitation/crystal formation depending on which specific agents are mixed[3][9].

Brand names

ReadySharp Anesthetics Plus BetamethasoneBetalido Kit

Other names

betamethasone sodium phosphate and betamethasone acetate with lidocaine or bupivacaineCelestone Soluspan plus local anesthetic