betamethasone dipropionate + betamethasone disodium phosphate + lidocaine

This drug is a combination of two forms of the corticosteroid betamethasone—betamethasone dipropionate and betamethasone disodium phosphate—with the local anesthetic lidocaine. Betamethasone is a potent synthetic glucocorticoid with anti-inflammatory and immunosuppressive properties, acting primarily by inhibiting multiple inflammatory cytokines and suppressing leukocyte migration. The dipropionate form is typically used for topical or intralesional administration due to its prolonged action, while the disodium phosphate form is water-soluble and suitable for rapid onset via injection. Lidocaine acts as a local anesthetic by blocking voltage-gated sodium channels in neuronal cell membranes, thereby preventing pain signal transmission. This combination may be used in clinical settings where both rapid and sustained anti-inflammatory effects are desired along with immediate pain relief, such as in musculoskeletal injections or certain dermatological procedures[1][2][8].

Brand names

DiprospanCelestone Soluspan

Other names

betamethasone dipropionate + betamethasone disodium phosphate + lidocaine 2%betamethasone dipropionate + betamethasone disodium phosphate-Hospital Alvorada-carpal tunnel syndrome