betamethasone dipropionate + clotrimazole + zinc oxide + petrolatum + menthol

**Betamethasone dipropionate + clotrimazole + zinc oxide + petrolatum + menthol** is a topical fixed-combination medication kit marketed as **Clobezin** by **Skya Health** for symptomatic inflammatory dermatophyte infections, including **tinea pedis, tinea cruris, and tinea corporis** in patients 17 years and older. The product contains two topical components: a **clotrimazole + betamethasone dipropionate cream** and a **zinc oxide paste** containing **menthol, white petrolatum, and zinc oxide**. Clotrimazole is an azole antifungal that disrupts fungal cell membrane integrity by inhibiting ergosterol synthesis, while betamethasone dipropionate is a corticosteroid that activates glucocorticoid signaling to suppress inflammatory and immune responses associated with symptomatic infection. The zinc oxide, petrolatum, and menthol paste functions mainly as a skin protectant and analgesic adjunct, helping soothe irritation and protect affected skin. Based on the provided context, the product is a small-molecule topical pharmaceutical and has been described in FDA labeling as an unapproved marketed drug product.

Brand names

Clobezin

Other names

clotrimazole + betamethasone dipropionate cream + zinc oxide + petrolatum + menthol pasteclotrimazole and betamethasone dipropionate cream with zinc oxide paste