Drug intelligence / Profile preview

betamethasone dipropionate + salicylic acid

Development stage
Unknown
Lead developer
Organon
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Administration
Topical
01

Overview

Betamethasone dipropionate + salicylic acid is a topical combination medication used to treat dry, scaly skin conditions such as psoriasis and eczema. Betamethasone dipropionate is a potent synthetic glucocorticoid corticosteroid that acts as an anti-inflammatory and immunosuppressive agent by reducing swelling, redness, and itching in the skin. Salicylic acid is a keratolytic agent (a type of salicylate) that softens and removes the outer layer of scales on the skin by increasing moisture content and dissolving intercellular "cement," thereby enhancing penetration of betamethasone to deeper layers. This combination provides both anti-inflammatory effects from the corticosteroid and enhanced descaling/penetration from the keratolytic action[1][2][6].

Brand names
DiprosalicRATIO-TopisalicBesoCare
Other names
betamethasone and salicylic acidbetamethasone dipropionate and salicylic acid
02

Targets

GR (Glucocorticoid receptor)

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