Drug intelligence / Profile preview

betamethasone dipropionate + urea

Development stage
Unknown
Lead developer
Merck
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Administration
Topical
01

Overview

Betamethasone dipropionate + urea is a topical combination medication used to treat inflammatory skin conditions such as eczema (atopic dermatitis) and psoriasis. Betamethasone dipropionate is a potent synthetic glucocorticoid corticosteroid that acts as an anti-inflammatory and immunosuppressive agent, reducing redness, swelling, and itching by inhibiting the production of pro-inflammatory mediators in the skin. Urea serves as a keratolytic agent, helping to remove dead tissue and enhance skin hydration, which accelerates healing and improves penetration of the corticosteroid. This combination is intended for external use only on affected areas of the skin[6]. It should be used with caution in certain populations (e.g., children under 13 years old, pregnant or breastfeeding women), and common side effects include local irritation such as redness or burning at the application site[6].

Other names
betamethasone + urea
02

Targets

GR (Glucocorticoid receptor)

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