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bevacizumab + cyclophosphamide + doxorubicin
- Development stage
- Phase 3
- Lead developer
- Genentech
- Modality
- Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
- Administration
- Intravenous
01
Overview
A combination therapy consisting of bevacizumab (a recombinant humanized monoclonal IgG1 antibody that inhibits vascular endothelial growth factor), cyclophosphamide (an alkylating agent), and doxorubicin (an anthracycline). This regimen has been studied primarily in breast cancer treatment, often administered as dose-dense doxorubicin-cyclophosphamide (ddAC) with bevacizumab, sometimes followed by additional agents like paclitaxel.
- Other names
- doxorubicin hydrochloride + cyclophosphamide + bevacizumab
02
Targets
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