Drug intelligence / Profile preview

Biejiajianwan (Beijing Ditan Hospital)

Development stage
Unknown
Lead developer
Sinopharm Wuhan ZhongLian SiYao Pharmaceutical
Administration
Oral
01

Overview

Biejiajianwan (also known as Biejiajian Pill) is a classic Traditional Chinese Medicine (TCM) formula first recorded in the ancient medical text *Synopsis of Prescriptions of the Golden Chamber* (*Jingui Yaolue*) by Zhang Zhongjing. Composed of 23 herbal and animal-derived ingredients, including *Carapax Trionycis* (turtle shell), donkey-hide gelatin, and various other botanical and insect components, Biejiajianwan is traditionally used to invigorate blood circulation, resolve phlegm, and soften hard masses. In modern clinical practice, it is developed and evaluated (often in combination with antiviral therapies like entecavir) for the treatment of chronic hepatitis B-related liver cirrhosis, liver fibrosis, and hepatocellular carcinoma (HCC). It is manufactured by companies such as Sinopharm Group Zhonglian Pharmaceutical.

Other names
BJJPBie Jia Jian WanBie-Jia-Jian-WanBiejiajian PillBiejiajian PillsBiejiajian Wan
02

Targets

LYN (LYN proto-oncogene, Src family tyrosine kinase)PDGFRB (Platelet-derived growth factor receptor beta)

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