Drug intelligence / Profile preview

bifidobacterium + lactobacillus (Wanze Shuangqi Pharmaceutical)

Development stage
Phase 2
Lead developer
ProbioTech
Modality
Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration
Oral, Intravaginal
01

Overview

A combination of live bacteria from the *Bifidobacterium* and *Lactobacillus* genera, this product is a live biotherapeutic used to modulate the gut microbiome. These probiotics work by helping to maintain the normal balance of microorganisms in the gastrointestinal tract, which can prevent the growth of harmful bacteria, improve intestinal barrier function, and modulate the immune system. Clinical studies have investigated its use in a variety of conditions, including the prevention of necrotizing enterocolitis in premature infants, tic disorders in children, antibiotic-associated diarrhea, hepatic encephalopathy in patients with liver cirrhosis, and improving outcomes in AIDS patients with intestinal disease. In China, a specific formulation known as "Bifidobacterium Lactobacillus triple viable tablets" (brand name Jinsuangqi or Shuangqi) is used in several clinical trials.

Brand names
JinsuangqiShuangqi
Other names
Live Combined Bifidobacterium and Lactobacillus tabletsBifidobacterium Lactobacillus triple viable tabletsbifidobacteria and Lactobacillus triplex viable tablets

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