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bifidobacterium bifidum + bifidobacterium longum + lactobacillus acidophilus + selenium
- Development stage
- Unknown
- Lead developer
- Kashan University of Medical Sciences
- Modality
- Small Molecules, Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Oral
01
Overview
bifidobacterium bifidum + bifidobacterium longum + lactobacillus acidophilus + selenium is a combination of three probiotic strains and the trace element selenium. It is primarily investigated for its neuroprotective and metabolic benefits in patients with Alzheimer's disease. The probiotics aim to modulate the gut-brain axis and reduce systemic inflammation, while selenium acts as a crucial cofactor for antioxidant enzymes like glutathione peroxidase to combat oxidative stress. Clinical studies have demonstrated that this co-supplementation can improve cognitive scores (MMSE), enhance insulin sensitivity, and improve lipid profiles in elderly patients with dementia.
- Other names
- probiotic and selenium co-supplementationprobiotic plus selenium
02
Targets
GPX4 (Glutathione peroxidase 4)
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