Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
**Bifidobacterium lactis HN019 + Lactobacillus acidophilus NCFM + Lacticaseibacillus rhamnosus HN001 + Lacticaseibacillus paracasei Lpc-37** is a multi-strain probiotic formulation typically marketed as a dietary supplement for improving gastrointestinal health and modulating immune function. Each strain contributes to digestive health by various mechanisms: - **Bifidobacterium lactis HN019**: Promotes gut motility, improves intestinal barrier, and modulates immune function by enhancing phagocytic and NK cell activity. It also increases levels of beneficial gut bacteria and may improve symptoms of constipation, diarrhea, bloating, and abdominal pain, likely by modulating the gut-brain axis and fermentation of short-chain fatty acids[1][2][3]. - **Lactobacillus acidophilus NCFM**: Well-characterized for promoting beneficial gut microbiota, improving lactose digestion, supporting immune function, and reducing gastrointestinal symptoms. - **Lacticaseibacillus rhamnosus HN001**: Known for enhancing both digestive and immune health, reducing atopic diseases, and reinforcing the gut barrier. - **Lacticaseibacillus paracasei Lpc-37**: Supports the balance of gut microbiota and enhances immune responses. The mechanism of action is primarily through modulation of gut microbiota composition, competition with pathogens, restoration of intestinal barrier function, production of short-chain fatty acids, and immune system enhancement. The product is generally developed for relief of digestive symptoms (such as constipation, diarrhea, bloating, IBS), maintenance of healthy gut microbiota, and supporting immune function[1][2][3].
Beyond the preview
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Follow clinical development from study design and recruitment through results.
Explore development by indication, patient population, and geography.
Trace asset ownership, licensing agreements, and commercial partnerships.
Explore the patent landscape and regulatory exclusivity around an asset.
Compare development programs by target, modality, and indication.
Connect source evidence and development news to your research questions.
See how Gosset can support your research on bifidobacterium lactis HN019 + lactobacillus acidophilus NCFM + lacticaseibacillus rhamnosus HN001 + lacticaseibacillus paracasei Lpc-37.