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Bio-Oss Collagen + HyaDent BG
- Development stage
- Unknown
- Lead developer
- Geistlich Pharma
- Administration
- Topical
01
Overview
Bio-Oss Collagen + HyaDent BG is a combination regenerative therapy used for the treatment of intrabony periodontal defects in patients with periodontitis. It consists of Bio-Oss Collagen, a xenogeneic bone substitute composed of bovine-derived bone mineral and a porcine collagen matrix, and HyaDent BG, a cross-linked hyaluronic acid gel of non-animal origin. The combination functions as a bioactive scaffold; Bio-Oss Collagen provides a stable environment for osteoconduction and long-term volume maintenance, while HyaDent BG promotes wound healing, reduces inflammation, and supports the regeneration of the periodontal ligament and alveolar bone. This combination is being studied as an alternative to enamel matrix derivatives (e.g., Emdogain) for improving clinical attachment levels and reducing probing pocket depths.
- Other names
- Bio-Oss Collagen + HyaDent BG
02
Targets
CD44 (CD44 antigen)
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