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BIO-THREE (TOA Biopharma)
- Development stage
- Unknown
- Lead developer
- TOA Biopharma
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Oral
01
Overview
BIO-THREE is a probiotic formulation developed and manufactured by TOA Biopharma. It contains three symbiotic active bacterial strains: Enterococcus faecium T-110, Clostridium butyricum TO-A, and Bacillus subtilis TO-A. These strains work synergistically to normalize the intestinal flora, promote the growth of beneficial bacteria (such as Bifidobacterium), and inhibit pathogenic microorganisms. Approved as a prescription drug in Japan since 1963, BIO-THREE is indicated for the treatment of gastrointestinal symptoms associated with dysbiosis, including constipation, diarrhea, and abdominal distension. It is also widely used as an over-the-counter (OTC) product, a veterinary feed additive, and a dietary supplement.
- Brand names
- BIO-THREEBIO-THREE HBIO-THREE HiBIO-THREE PZProbiotic-3Probiotic3Probiotic 3ビオスリービオスリーHビオスリーHi錠
- Other names
- BIO-THREE probioticBIO-THREE probiotic powder formulationBIOSURI
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