Drug intelligence / Profile preview

biphasic insulin aspart 70 (Novo Nordisk)

Development stage
Discontinued
Lead developer
Novo Nordisk
Modality
Peptides
Administration
Subcutaneous
01

Overview

Biphasic insulin aspart 70 (BIAsp 70) is a premixed insulin analog formulation developed by Novo Nordisk for the management of blood glucose levels in patients with diabetes mellitus. It consists of a mixture of 70% soluble insulin aspart, which provides a rapid onset of action to control postprandial glucose excursions, and 30% insulin aspart crystallized with protamine, which provides an intermediate-acting basal component. This specific ratio (70/30 rapid-to-intermediate) is designed to provide intensive prandial coverage. BIAsp 70 was part of the NovoMix product line (marketed as NovoMix 70), which also included BIAsp 30 and BIAsp 50. While BIAsp 30 became the standard of care in many regions, BIAsp 70 was primarily used in specific clinical scenarios requiring intensive mealtime coverage and was eventually withdrawn from several markets, including the European Union, for commercial reasons.

Brand names
NovoMix 70NovoMix70NovoMix-70
Other names
70% insulin aspart and 30% insulin aspart protamineBiphasic insulin aspart 70/30
02

Targets

INSR (Insulin receptor)

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