Drug intelligence / Profile preview

bisoprolol + ramipril

Development stage
Unknown
Lead developer
Neopharmed Gentili
Modality
Small Molecules
Administration
Oral
01

Overview

Bisoprolol + ramipril is a fixed-dose combination (FDC) therapy that combines a beta-blocker (bisoprolol) with an angiotensin-converting enzyme (ACE) inhibitor (ramipril). This combination targets different blood pressure control systems with complementary mechanisms of action. The FDC format is designed to reduce tablet burden, improve treatment adherence, and enhance blood pressure control in patients with hypertension. Clinical studies have demonstrated bioequivalence for the 10/5 mg strength and the absence of clinically relevant pharmacokinetic drug-drug interactions between bisoprolol and ramipril[1][5].

Brand names
RamiBiso APONTIS
Other names
ramipril/bisoprololbisoprolol/ramipril
02

Targets

ADRB1 (β1)ACE (Angiotensin Converting Enzyme)

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