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bivalent oral poliovirus vaccine (Centers for Disease Control and Prevention)
- Development stage
- Unknown
- Lead developer
- Centers for Disease Control and Prevention
- Modality
- Vaccines & Immunotherapeutics
- Administration
- Oral
01
Overview
bOPV (bivalent oral poliovirus vaccine) is a live-attenuated vaccine used for the prevention of poliomyelitis. It contains Sabin strains of poliovirus types 1 and 3. Introduced globally in 2016 to replace the trivalent oral poliovirus vaccine (tOPV) following the eradication of wild poliovirus type 2, bOPV is a critical tool in the Global Polio Eradication Initiative. The vaccine works by inducing both systemic (humoral) and intestinal (mucosal) immunity, which is essential for preventing person-to-person transmission of the virus. It is typically administered as oral drops and is used in routine childhood immunization schedules and mass vaccination campaigns.
- Brand names
- Polio Sabin One and ThreeBOPV
- Other names
- bivalent oral polio vaccineSabin types 1 and 3 oral poliovirus vaccine
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