Drug intelligence / Profile preview

black cumin seed oil + omega-3 fatty acids

Development stage
Unknown
Lead developer
TriNutra
Modality
Small Molecules
Administration
Oral
01

Overview

A combination of black cumin seed oil (derived from *Nigella sativa*) and omega-3 fatty acids (typically EPA and DHA) investigated for its immunomodulatory and anti-inflammatory properties. Black cumin seed oil contains the bioactive compound thymoquinone, which exhibits antioxidant effects and inhibits pro-inflammatory pathways such as NF-κB and COX-2. Omega-3 fatty acids further contribute to the reduction of systemic inflammation by serving as substrates for anti-inflammatory lipid mediators. This combination is primarily explored as a supportive therapy to enhance immune function and mitigate the inflammatory response associated with viral infections like COVID-19, as well as in metabolic and cardiovascular conditions.

Brand names
ThymoQuinOmega-3 Black Seed OilOmega3 Black Seed OilOmega 3 Black Seed OilNature's Answer Omega-3 Black Seed Oil
Other names
Nigella sativa oil + omega-3thymoquinone + omega-3 fatty acidsblack cumin seed oil + omega 3
02

Targets

AMPK (Adenosine monophosphate–activated protein kinase)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)NF-κBTNFA (Tumor necrosis factor alpha (soluble))

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